Craig Porter, PhD
Department of Pediatrics
Division of Developmental Nutrition
The overall goal of our research program is to better understand the role of the the mitochondrion in health and disease. Areas of focus include studying the role of mitochondrial proton leaks in the regulation of metabolic rate, as well as studying the impact of lifestyle (i.e. diet/exercise) and pharmacological interventions on bioenergetics in several settings including developmental programming, obesity and trauma. With a strong focus on metabolic physiology, we use a wide range of techniques such as respiratory gas exchange and stable isotope approaches to determine metabolic rate and substrate metabolism at a whole body level, as well as laboratory techniques including high-resolution respirometery, flurometry and spectrophotometry to assay tissue and cell mitochondrial function.