Bone Structure & Histomorphometry

Bone Structure & Histomorphometry Facility

The ACNC Bone Structure & Histomorphometry Facility offers tools to enable a comprehensive evaluation of gross skeletal and histological bone parameters for clinical and basic research studies. The laboratory has capabilities to assess bone mass and architectural properties (bone mineral density, content and strength) using micro-CT (SkyScan 1272 High Resolution Micro-CT). The facility is also equipped with an OsteoMeasure™ Histomorphometry System (OsteoMetrics™, Inc.) with Olympus Dotslide motorized microscope system. The system is used by trained laboratory personnel to generate static and dynamic histomorphometric data based on ASBMR-standardized parameters. The Facility assets are complemented by two Stratec XCT peripheral Quantitative Computed Tomography (pQCT) instruments that enable measurement of bone parameters of the peripheral skeleton (e.g. radius, tibia and femur) to be investigated in detail (for human and animal studies). Other assets for bone research at ACNC include a dual-energy X-ray absorptiometry (DEXA) and bone magnetic resonance imaging (MRI) system.